If you would like to be included in our research database, please feel free to contact us at:

Email: ra@clinicalneurosciencelab.com
Phone: 614-292-9568

















Interventions to Improve Cognitive Functioning in Multiple Sclerosis

Do you have trouble keeping track of your thoughts or remembering things?

The Clinical Neuroscience Laboratory at The Ohio State University is conducting a 6-month (minimal involvement) intervention study to potentially improve thinking in those with multiple sclerosis. Everyday factors such as exercise, water-intake, sleep, nutrition and social support play a role in cognitive functioning. For this study, participants will be asked to track their water-intake or physical activity. As part of this study, you will undergo five assessment sessions, each lasting between 2.5 to 3.5 hours. You will also participate in a 6-month behavior-monitoring period requiring minimal time commitment (no more than five minutes/day). Monetary compensation and free parking will be provided for all assessment sessions. Participants will also receive an activity tracker like a Fitbit OR a water-intake tracker. Here are the details on the study components:

  1. 1.The first assessment session will examine your thinking abilities using computerized and paper and pencil tasks. We will also ask that you fill out some questionnaires regarding your emotional and physical health on the computer. This session will be repeated midway through the 6-month monitoring period and after the completion of the monitoring period. This session is tailored to your schedule, including nights and

    weekends, and will last approximately 3.5 hours. You will be compensated $10 / hour for your time.

  1. 2.The second assessment session will involve an MRI scan and a blood draw. Participants who do not meet eligibility requirements for the MRI environment will not participate in the MRI scan portion of the study. During the scan, you will complete some active tasks and some passive resting scans. This session will be repeated after the completion of the monitoring period. This scan will last approximately 75 minutes and the blood draw will last approximately 15 to 30 minutes. The whole session will last approximately 3 hours. There will also be a short break following the first portion of the session. Again, this visit can be tailored to your schedule and you will be compensated $15 / hour.

  2. 3.Between the first and second assessment sessions, you will be asked to wear and activity-monitoring device for 7-days. You will also be given a water bottle that tracks your water intake to use during the 7 days. We will ask that you go about your daily routine as usual and make a few notes about your behavior during those days, requiring a minimal time commitment of 5 minutes / day.

  3. 4.After assessment has been completed, you will be randomized to one of two study groups (similar to flipping a coin) and provided with behavior monitoring equipment.

If you are interested, please check the eligibility criteria to see if you qualify for this study:

Between the ages of 30-59

Clinically definite diagnosis of relapsing-remitting multiple sclerosis (RRMS)

Absence of any other neurological or psychiatric diagnoses besides RRMS

Absence of relapse or high-dose corticosteroid use at least 30 days prior to your first assessment

If these criteria fit you, and you are interested in participating please complete this screening survey!

OR – You can contact the study coordinator at ra@clinicalneurosciencelab.com or 614-292-9568 to complete a brief phone interview and schedule your first session. If you have further questions at this time please feel free to contact us directly and we will provide any additional answers. We look forward to hearing from you!


Email: ra@clinicalneurosciencelab.com
Phone: 614-292-9568